Table 1. Concentrations of secreted human EPO protein over time as measured via ELISA analysis (as depicted in Figure 1).
Time post administration (h) | Secreted human EPO protein (ng ml−1) |
---|---|
0.50 | 188 |
3 | 10 125 |
6 | 11 296 |
12 | 8521 |
24 | 6114 |
48 | 341 |
72 | 47.0 |
1 week | 0.12 |
Abbreviations: ELISA, enzyme-linked immunosorbent assay; EPO, erythropoietin.
EPO mRNA (1.0 mg kg−1) was delivered via C12-200-based lipidoid nanoparticles. Values are depicted as ng of human EPO protein per ml of serum.