LIF2 Functions Mainly as a Transcriptional Activator on Its Targets.
(A) to (F) Venn diagrams between genes of LIF2 ERs ([A] and [D]), LIF2-LHP1 IRs ([B], [E], and [G]), and LHP1 ERs ([C] and [F]) and deregulated genes in vegetative tissues of the lif2 ([A] to [C]) and lhp1 ([D] to [F]) mutants. The analysis involved genes for which the binding was located in coding sequences or in UTRs.
(G) Comparisons between target genes and deregulated genes in lif2 and lhp1 mutants.
(H) Venn diagram and GO annotations of LHP1-LIF2 IR genes and genes activated by LHP1 and LIF2, respectively, revealed a small set of genes that requires a synergistic and activation function of both LIF2 and LHP1.