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. 2016 Sep 1;7(9):e2356. doi: 10.1038/cddis.2016.259

Figure 6.

Figure 6

ANXA1 coregulates the expression of Bid with p53. (a) qPCR results showing the expression of Bid mRNA after treatment with PFT-α. The data are expressed as the means±S.E.M. from three independent experiments. *P<0.05 versus control and #P<0.05 versus OGD/R. (b) Western blot showing expression of the Bid protein after treatment with PFT-α in primary cultured neurons or HEK293 cells. (c) Statistical analysis of the data shown in (b). The data are expressed as the means±S.E.M. from three independent experiments. *P<0.05 versus control and #P<0.05 versus OGD/R. (d) Statistical analysis of qPCR results showing the expression of Bid mRNA after treatment with ANXA1 and PFT-α. The data are expressed as the means±S.E.M. from three independent experiments. *P<0.05 versus control, #P<0.05 versus OGD/R and &P<0.05 versus ANXA1+OGD/R. (e) Western blot showing expression of the Bid protein after treatment with ANXA1 and PFT-α in primary cultured neurons or HEK293 cells. (f) Statistical analysis of the data shown in (e). The data are expressed as the means±S.E.M. from three independent experiments. *P<0.05 versus control, #P<0.05 versus OGD/R and &P<0.05 versus ANXA1+OGD/R. (g) Statistical analysis of the qPCR results shows the expression of Bid mRNA after treatment with ANXA1 shRNA and PFT-α. The data are expressed as the means±S.E.M. from three independent experiments. *P<0.05 versus control, #P<0.05 versus OGD/R and &P<0.05 versus ANXA1 shRNA+OGD/R. (h) Western blot showing expression of the Bid protein after treatment with ANXA1 shRNA and PFT-α. (i) Statistical analysis of the data shown in (h). The data are expressed as the means±S.E.M. from three independent experiments. *P<0.05 versus control, #P<0.05 versus OGD/R and &P<0.05 versus ANXA1 shRNA+OGD/R