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. 2016 Sep 1;7(9):e2358. doi: 10.1038/cddis.2016.262

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Copyright © 2016 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Jarid1b is overexpressed in the moderate and high-differentiated HPSCC. (a) Measurement of Jarid1b mRNA expression for the divided groups by quantitative RT-PCR. L: low-differentiated HPSCC (n=10), H/M: moderate and high-differentiated HPSCC (n=24). **P<0.01, Student's t-test. (b) JARID1B and K10 proteins were detected by immunoblotting in the H/M-differentiated HPSCC (HPC) and adjacent normal tissue (ANT). (c) Representative images of immunohistochemical staining for JARID1B, K10 and Ki67 in L and H/M-differentiated human HPSCC. K10 showed no obvious staining in cytoplasm in low-differentiated HPSCC. All scale bars are 100 μm. (d) Quantifications were provided and showed high JARID1B expression and low Ki67-positive percentage in the H/M HPSCC. **P<0.01, Student's t-test