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. 2016 Sep 8;7(9):e2364. doi: 10.1038/cddis.2016.267

Figure 1.

Figure 1

DNase I hypersensitive (DHS) site analysis of the c-myb locus in M1 and differentiated M1 cells. Nuclei from both M1 cells and IL-6-treated M1 cells were subjected to a limited DNase I digestion. Fractions containing small DNA fragments representing two-hit DNase I cutting events were precipitated, pooled, and prepared for paired-end sequencing. DHS-seq data of the c-myb locus are shown by the reads density created by the Seqmonk software in M1 and differentiated M1 cells. Red dashed box shows detected DHS site located at the −28 region during IL-6-induced differentiation. TSS, transcription start site