Table 2.
Relative risks of systemic sclerosis and other autoimmune diseases for individuals with affected first-degree relatives
| Autoimmune diseases | With affected relatives | General population | Relative risk (95 % CI)a | ||
|---|---|---|---|---|---|
| No. of cases | Prevalence (%) | No. of cases | Prevalence (%) | ||
| Systemic sclerosis | 3 | 0.08 | 1891 | 0.008 | 13.23 (3.11–56.33) |
| Rheumatoid arthritis | 11 | 0.29 | 37,482 | 0.16 | 2.64 (1.46–4.75) |
| Systemic lupus erythematosus | 20 | 0.53 | 18,915 | 0.08 | 6.51 (4.05–10.46) |
| Sjögren’s syndrome | 4 | 0.11 | 12,754 | 0.05 | 2.77 (1.04–7.35) |
| Idiopathic inflammatory myositis | 2 | 0.05 | 1808 | 0.01 | 8.05 (2.03–31.92) |
| Type I diabetes mellitus | 5 | 0.13 | 10,281 | 0.04 | 2.51 (0.90–7.07) |
| Multiple sclerosis | 1 | 0.03 | 1252 | 0.01 | 5.16 (0.73–3665) |
| Psoriasis | 47 | 1.24 | 196,333 | 0.83 | 1.52 (1.15–2.01) |
a Adjusted for age, gender, place of residence, quintiles of income levels, occupations, and family size