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. 2016 Oct 12;18:234. doi: 10.1186/s13075-016-1130-y

Table 3.

Associations between IPFP hypointense signals and baseline bone marrow lesions and increases in bone marrow lesions over 2.6 years

Multivariablea Multivariableb
OR (95 % CI) OR (95 % CI)
Baseline bone marrow lesions
 Any bone marrow lesions 1.64 (1.32, 2.03) 1.11 (0.87, 1.42)
 Medial tibiofemoral 1.77 (1.39, 2.25) 1.24 (0.95, 1.63)
 Lateral tibiofemoral 1.40 (1.08, 1.80) 1.03 (0.78, 1.36)
 Patellar 1.21 (0.93, 1.57) 0.83 (0.61, 1.13)
Increases in bone marrow lesions
 Any bone marrow lesions 1.91 (1.39, 2.62) 1.45 (1.02, 2.04)
 Medial tibiofemoral 2.11 (1.46, 3.07) 1.59 (1.06, 2.39)
 Lateral tibiofemoral 1.66 (1.17, 2.35) 1.36 (0.93, 1.97)
 Patellar 1.50 (1.04, 2.15) 1.34 (0.92, 1.95)

Dependent variables: baseline bone marrow lesions or increases in bone marrow lesions (yes v no); independent variables: IPFP hypointense signals (per grade)

IPFP infrapatellar fat pat

aAdjusted for age, sex, BMI, and radiographic osteoarthritis

bFurther adjustment for cartilage defects