Table 3.
Cox multivariate analyses of prognostic factors on patients’ survival
| Variables | Hazards ratio | 95 % CI | P value |
|---|---|---|---|
| Cancer-specific survivala | |||
| CA19-9, U/ml (≤35 v >35) | 1.553 | 0.904–2.668 | 0.111 |
| Tumor size, cm (≤5.5 v >5.5) | 2.143 | 1.239–3.706 | 0.006 |
| Nodal metastasis (absent v present) | 1.390 | 0.703–2.749 | 0.343 |
| Vascular invasion (absent v present) | 1.954 | 1.181–3.233 | 0.009 |
| TNM (I-II v III-IV) | 0.884 | 0.459–1.702 | 0.711 |
| Serum CRP, mg/L (≤1.8 v >1.8) | 2.646 | 1.356–5.164 | 0.004 |
| Recurrence- free survivalb | |||
| Postoperative chemotherapy (yes v no) | 1.788 | 1.042–3.067 | 0.035 |
| Tumor size, cm (≤5.5 v >5.5) | 1.920 | 1.153–3.197 | 0.012 |
| Nodal metastasis (absent v present) | 1.277 | 0.689–2.367 | 0.437 |
| Vascular invasion (absent v present) | 1.733 | 1.107–2.715 | 0.016 |
| TNM (I-II v III-IV) | 0.663 | 0.369–1.191 | 0.169 |
| Serum CRP, mg/L (≤1.8 v >1.8) | 2.827 | 1.636–4.886 | < 0.001 |
CI confidence interval, CA19-9 carbohydrate antigen 19-9, TNM tumor-node-metastasis, CRP C-reactive protein
aThe total number of patients and total number of events in this model were 140 and 67, respectively
bThe total number of patients and total number of events in this model were 140 and 87, respectively