Table 4.

Multivariate predictors of ‘definitely wanting’ a screening test for cancer for scenarios 1 to 5

Variable	Unadjusted odds ratio (95% CI)	P‐value	Adjusted odds ratio (95% CI)	P‐value
Scenario 1
Age (years)*	1.06 (1.02–1.09)	<0.001	1.05 (1.02–1.09)	0.002
50–59†	1.00		1.00
60–70	1.93 (1.32–2.82)		1.85 (1.25–2.73)
Educational qualifications
Without SC	1.77 (1.01–3.11)	0.009	1.43 (0.80–2.55)	0.03
SC/TAFE/HSC	1.89 (1.23–2.91)		1.78 (1.15–2.74)
University qualification†	1.00		1.00
Scenario 2
Age (years)	1.04 (1.01–1.08)	0.01	NA	NA
50–59†	1.00
60–70	1.56 (1.07–2.29)
Scenario 3
Educational qualifications
Left before SC	1.69 (0.99–2.88)	0.02	1.57 (0.90–2.75)	0.03
SC/HSC/TAFE	1.74 (1.16–2.61)		1.71 (1.14–2.57)
University degree†	1.00		1.00
Employment status
Not employed	1.67 (1.13–2.45)	0.01	1.60 (1.07–2.39)	0.02
Employed†	1.00		1.00
Current smoker
Yes†	1.00	0.09	1.00	0.051
No	1.55 (0.93–2.59)		1.67 (0.99–2.82)
Scenario 4
Age (years)	1.05 (1.02–1.09)	0.002	1.05 (1.01–1.08)	0.02
50–59†	1.00		1.00
60–70	1.79 (1.22–2.62)		1.68 (1.14–2.48)
Self‐reported health status
Excellent/good†	1.00	0.006	1.00	0.007
Fair/poor	1.81 (1.19–2.74)		1.66 (1.08–2.53)
Scenario 5
Age (years)	1.07 (1.03–1.11)	<0.001	1.07 (1.03–1.10)	0.001
50–59†	1.00		1.00
60–70	2.23 (1.45–3.42)		2.13 (1.38–3.29)
Has ever had heart attack or stroke
Yes	2.35 (1.22–4.52)	0.01	1.98 (1.01–3.86)	0.052
No†	1.00		1.00

*Age was modeled as a continuous variable. Age is also presented as a categorical variable to facilitate interpretation of the effect age has on the outcomes’.

^†Referent group.

Scenario 1, lack of evidence underpinning efficacy of screening; scenario 2, risk of detecting indolent cancer; scenario 3, lifetime risk of dying from cancer; scenario 4: lack of expert consensus on the efficacy of early detection; scenario 5, uncertainty of benefit from treatment and risk of developing side‐effects from treatment.