Figure 6. Assessment of antiviral drugs in HepBHAe82 cells.
(A) Schematics of HBV replication steps and antiviral targets in HepBHAe82 cells. (B) Upon withdrawal of tet, HepBHAe82 cells were treated with Bay41-4109 (2 µM), AT-61 (25 µM), and 3TC (10 µM) for 6 days. The compound treatment was repeated every two days. Intracellular viral RNA, core protein, capsid particles, encapsidated pgRNA, and core DNA, were analyzed.