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. 2016 Oct 31;1(3):e574. doi: 10.1097/PR9.0000000000000574

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Copyright © 2016 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike License 4.0 (CCBY-NC-SA), which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Figure 1. — Experimental design. (A) Timeline of the experiment. The experiment started with a thirst (visual analog scale) and mood rating (Multidimensional Mood Questionnaire). This rating was repeated 7 times during the experiment. A baseline pain test was administered before participants were randomized into either thirst or control group. After a waiting period, a second pain test was completed. All participants were then provided with water ad libitum to eliminate their thirst. After 30 mins, a last pain test was completed. (B) Trial structure. Each trial started with a variable intertrial interval (ITI). A heat pain stimulus was then applied while the fixation crosshair remained unchanged on the screen. After a variable delay, participants had 10 seconds to provide their pain rating on a visual analog scale.