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Summary of dual labeled HPMA copolymer conjugates.
| No | Polymer precursor | Dual-labeled conjugate | Mw kDa | Mw/Mn | EPI (wt%) | DTPA |
Label isotode |
|
|---|---|---|---|---|---|---|---|---|
| No./per chain | Backbone | EPI | ||||||
|
I
II |
P-DTPA-EPI(Tyr) | 111In-P-EPI-125I | 28.2 | 1.07 | 10.5 | 3.7 | 111In | 125I |
|
III
IV |
2P-DTPA-EPI(Tyr) | 111In-2P-EPI-125I | 65.8 | 1.20 | 9.7 | 4.5 | 111In | 125I |
|
V
VI |
2P-Tyr-EPI(DTPA) | 125I-2P-EPI-111In | 75.2 | 1.25 | 5.5 | 1 | 125I | 111In |
