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. Author manuscript; available in PMC: 2017 Apr 28.
Published in final edited form as: J Med Chem. 2016 Apr 6;59(8):3635–3649. doi: 10.1021/acs.jmedchem.5b01718

Figure 2.

Figure 2

Comparison of total tube length (A) and total tube junctions (B) for ITZ, 2, 18, and 21. DMSO (negative control) was set as 100% tube formation for analysis purposes. Suramin (10 μM) was used as the positive control for each experiment and its ability to inhibit tube length (51.9 ± 7.8%) and tube junctions (57.6 ± 6.1%) was consistent. Data represent the Ave ± SEM of at least 3 separate experiments in which ≥ 5 fields of vision were quantified using ImageJ software.