Figure 2.
Comparison of total tube length (A) and total tube junctions (B) for ITZ, 2, 18, and 21. DMSO (negative control) was set as 100% tube formation for analysis purposes. Suramin (10 μM) was used as the positive control for each experiment and its ability to inhibit tube length (51.9 ± 7.8%) and tube junctions (57.6 ± 6.1%) was consistent. Data represent the Ave ± SEM of at least 3 separate experiments in which ≥ 5 fields of vision were quantified using ImageJ software.