TABLE 1.
Descriptive characteristics of cohort 1 (original) and cohort 2 (new).
| No. (%) or median | |||
|---|---|---|---|
| Characteristics | Cohort 1 (n = 78) | Cohort 2 (n = 62) | p value* |
| Median age at diagnosis (range), y | 62 (37–81) | 59 (38–82) | .15 |
| Follow-up time (range), mo | 54 (1–85) | 26 (5–54) | <.01 |
| Sex: male/female | 56 (72)/22 (28) | 51 (82)/11 (18) | .15 |
| Lymph node stage treated (n = 129) N0/N+ | 25 (32)/53 (68) | 12 (24)/39 (76) | .30 |
| Primary tumor stage (n = 135) 1 or 2/3 or 4 | 38 (49)/40 (51) | 31 (54)/26 (46) | .52 |
| Disease site condensed (n = 134) | |||
| Oral cavity | 4 (5) | 0 (0) | |
| Oropharynx | 42 (54) | 37 (66) | |
| Hypopharynx | 4 (5) | 5 (9) | |
| Larynx | 28 (36) | 14 (25) | .13 |
| Median RT duration, d | 51 (39–83) | 46 (38–67) | <.01 |
| RT duration | |||
| ≤56 d | 64 (82) | 58 (94) | |
| ≥57 d | 14 (18) | 4 (6) | .04 |
| Median pretreatment Hgb, (range) g/dL | 13.50 (9–17.10) | 14 (8.6–19.40) | .17 |
| Pretreatment Hgb, g/dL | |||
| <12 | 18 (23) | 9 (15) | |
| ≥12 | 60 (77) | 53 (85) | .20 |
| Median pretreatment weight, (range) kg | 79.75 (46.80–141) | 81.75 (42.60–125.50) | .39 |
| Pretreatment weight status | |||
| <90% IBW | 14 (18) | 6 (10) | |
| ≥90% IBW | 64 (82) | 56 (90) | .23 |
| Locoregional progression: no/yes | 63 (81)/15 (19) | 59 (95)/3 (5) | .01 |
| Locoregional failure type, recurrent/persistent | 4/10 | 0/3 | .03 |
Abbreviations: RT, radiation therapy; Hgb, hemoglobin; g/dL, grams per deciliter; kg, kilograms; IBW, ideal body weight.
*
Chi-square (2-tailed) was used to examine differences for categorical variables and Mann–Whitney U test (2-tailed) was used to examine differences for continuous variables.