Table 2.
Immunization | Frequency (%)
|
|
---|---|---|
WT | null | |
Non- Immunization | 3.0 ± 1.4 | 3.7 ±2.4 |
DNP-KLH (day 28) | 43.5 ± 1.8 | 40.8 ± 2.1 |
mPGES-1 WT and null mice were injected i.p. with T-cell dependent (TD) antigen DNP-KLH in CFA on day 0 and challenged with antigen in IFA on day 21. Spleens from mice of mPGES-1 null and WT mice on day 28 were assessed for frequency (%) of PNA positive germinal centers to IgD positive regions. Values represent the mean percentage ± SEM (n=3–4). Differences between mPGES-1 null mice and WT littermates were not significant (Student’s t-test)