Table 1. IL-10 and IL-12 are key regulators of IFN-γ in macrophage: T cell cultures while IL-6 does not contribute significantly to T cell biasing in this system.

		Classical macrophages	Type II macrophages
IL-10	Neutralise	↑IFN-γ, ↑IL-12	↑IFN-γ, ↑IL-12
	rIL-10	↓IFN-γ, ↓IL-12, ↓IL-17A	↓IFN-γ, ↓IL-12
IL-12	Neutralise	↓IFN-γ	↓IFN-γ, ↓IL-17A
	rIL-12	No change	↑IFN-γ
IL-6	Neutralise	No change	No change
	rIL-6	No change	No change