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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Inorganica Chim Acta. 2016 Jan 16;452:3–11. doi: 10.1016/j.ica.2016.01.021

Figure 1.

Figure 1

Four common binding modes of small molecules to DNA: (a) covalent binding, (b) intercalation, (c) groove binding, and (d) insertion. Structural data from PDB files 1AIO, 454D, 2LWH, and 3GSK.