Table 3.

Adjusted associations between seafood consumption and performance on neuropsychological screening battery(n=513 participants with 1502 observations).

	Consumer Group					Avg. Razor Clam DA Exposure
	None	Low		High
	Coef.	Coef.	p-valueg	Coef.	p-valueg	Coef.k	p-valueg
WAIS-III Digit Symbol Coding
Age-corrected	Ref.	−0.10	0.46	−0.29	0.08	−0.47	0.27
WAIS-III Block Design
Age-corrected	Ref.	+0.07	0.61	−0.21	0.22	−0.47	0.30
WAIS-III Digit Span
Age-corrected	Ref.	−0.05	0.67	−0.11	0.49	−0.13	0.74
CVLT Trial 5 Free Recall
T score	Ref.	−0.57	0.38	−1.67	0.04	−2.28	0.28
CVLT Short Delay Free Recall
T score	Ref.	−0.50	0.38	−1.40	0.05	−1.56	0.41
CVLT Long Delay Free Recall
T score	Ref.	−0.10	0.87	−0.65	0.41	−2.61	0.20
Trailmaking Test: Part A
T score	Ref.	+0.09	0.89	−0.18	0.82	−1.15	0.59
Trailmaking Test: Part B
T score	Ref.	−0.45	0.44	+0.24	0.75	+1.65	0.39
Laf. Grooved Pegboard, Dom. Hand
T Score	Ref.	+0.05	0.94	−1.13	0.18	−3.96	0.08
Laf. Grooved Pegboard, Non-dom. Hand
T Score	Ref.	+0.20	0.75	−0.21	0.79	−0.11	0.96
Beck Depression Inventory-II
Raw score	Ref.	−1.10	0.04	−1.32	0.05	−1.48	0.41
State Trait Anxiety Inventory
State: Age-corrected	Ref.	−0.75	0.26	−0.99	0.23	−1.70	0.44
Trait: Age-corrected	Ref.	−0.80	0.24	−1.39	0.10	−3.30	0.14

Adjusted for age, sex, race (Native American or not), tribe, year, education level, and employment status.

^gGeneralized estimating equations, accounting for repeated measures.

^kCoefficients for “number of razor clams consumed per month” are multiplied by one thousand.

Razor clam consumption groups were averaged over fall/winter and spring/summer:

• None: Did not consume razor clams that year
• Low: Consumed fewer than 15 razor clams per month
• High: Consumed at least 15 razor clams per month

Razor clam Domoic Acid exposure: Calculated as: (average number of razor clams consumed per month) time (average concentration, in parts per million, of Domoic Acid in razor clams at the beach(es) from which the participant ate clams that year.)