Table 1.
Participant demographics and MoCA performance
| N | Age M (SD) years | Gender F/M | Caucasian (%) | Education M (SD) years | MoCA score M(SD) (range 0–30) | s-MoCA* score M(SD) (range 0–16) | |
|---|---|---|---|---|---|---|---|
| All neurological diagnoses† | 1675 | 70.00 (10.15) | 783/888 | 85 | 15.12 (3.37) | 21 (7) | 9 (4) |
| AD | 354 | 75.96 (8.19) | 228/126 | 71 | 13.71 (3.90) | 14 (6) | 5 (3) |
| MCI | 117 | 73.50 (8.81) | 59/58 | 79 | 14.95 (3.66) | 21 (4) | 9 (3) |
| PD | 690 | 64.84 (9.68) | 267/423 | 94 | 15.99 (2.65) | 25 (4) | 12 (3) |
| PD-dementia‡ | 91 | 70.66 (8.34) | 27/63 | 92 | 15.50 (2.70) | 21 (5) | 9 (4) |
| HC | 175 | 71.96 (9.34) | 116/59 | 80 | 16.02 (2.71) | 27 (2) | 14 (2) |
All significant pairwise comparisons p<0.01.
Age: HC>all neuro; HC<AD; HC>PD; AD>MCI; MCI=HC; PD<PDD.
Sex: HC≠all; HC=AD; AD≠MCI; MCI≠HC; PD≠HC; PD=PDD.
Race: HC=all neuro=MCI; AD≠HC; AD=MCI; PD≠HC; PD=PDD.
Education: HC>all neuro, AD, and MCI; HC=PD=PDD.
MoCA: HC>all neuro, AD, MCI, PD, and PDD; MCI>AD; PD>PDD.
s-MoCA: HC>all neuro, AD, MCI, PD, and PDD; MCI>AD; PD>PDD.
Maximum score=16.
All individuals with at least one neurological condition. 220 individuals had other neurological diagnoses (see figure 2); 107 individuals qualified for multiple clinical diagnoses; 96 individuals were not healthy, but had indeterminate diagnosis at the time of MoCA testing.
Dementia in PDD participants was determined either through a consensus process19 criteria for PDD, or was made by an experienced movement disorders neurologist.
AD, Alzheimer’s disease; F, female; HC, healthy control; M, male; MCI, mild cognitive impairment; MoCA, Montreal Cognitive Assessment; PD, Parkinson’s disease; PDD, PD with dementia; s-MoCA, short form MoCA.