Time course of the response in mice after treatment with vehicle (coin oil) and FLU (200 mg/kg). (A) Changes in liver weights. (B) Changes in liver weight/body weight ratios. (C-G) Ahr (C) and battery genes, Cyp1a1 (D), Cyp1a2 (E), Nqo1 (F), and Gsta1 (G) mRNA expression. Data are presented as mean ± SEM; n = 6/group. *P < 0.05, and **P < 0.01 versus vehicle group, by two-tailed Student’s t-test test.