Table 1.
Functional category | Strain(s) | Predicted function of disrupted or identified locus | Competition Defect | Reference |
---|---|---|---|---|
Complement resistance | > 30 isolates | Multiple loci | +, ++, +++ | Silver et al., 2007b |
Oxidative stress response | JG186 | (KatA) | – | Rio et al., 2007 |
Surface modification | JG535 | Glycosyltransferase, type 1 capsular polysaccharide synthesis | +++ | Silver et al., 2007b |
JG730 JG736 | Murein lipoprotein (lpp) | +++ | Silver et al., 2007b | |
JG735 | 3-deoxy-D-manno-octulosonic-acid transferase | +++ | Silver et al., 2007b | |
JG738 | Polysaccharide synthesis protein/Glycosyltransferase (WbbB) | ++ | Silver et al., 2007b | |
Regulatory | JG547 | Ribosomal operon | + | Silver et al., 2007b |
JG697 | GTPase (YchF) | ++ | Silver et al., 2007b | |
JG741 | RNase II | + | Silver et al., 2007b | |
Nutrition | JG537 | Phosphate ABC transporter (PstC) | ++ | Silver et al., 2007b |
JG698 | ZIP family metal transporter (ZupT) | + | Silver et al., 2007b | |
JG750 | Threonine/serine transporter (TdcC) | ++ | Silver et al., 2007b | |
Host interaction | JG752 | T3SS apparatus (AscU) | ++ | Silver et al., 2007a |
JG573 | T6SS effector, Rearrangement hotspot protein (Rhs) | +++ | Silver et al., 2007b | |
HE-1095 | T2SS apparatus (ExeM) | + | Maltz and Graf, 2011 | |
Unknown | JG521 JG523 JG538 | Hypothetical proteins | + | Silver et al., 2007b |
JG532 | MBL-fold metallo-hydrolase domain containing protein | + | Silver et al., 2007b | |
JG533 | KAP family P-loop NTPase protein | + | Silver et al., 2007b | |
JG751 | Intergenic region; upstream of predicted GTPase | + | Silver et al., 2007b | |
JG753 | Intergenic region; upstream of hypothetical protein | + | Silver et al., 2007b | |
Competition defect of Aeromonas isolates in the leech crop relative to the parent strain is indicated as follows: –, no colonization deficiency; +, 2–10 fold deficiency; ++, 10–100 fold deficiency; +++, >100 fold deficiency.