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. 2016 Oct 13;7:425. doi: 10.3389/fimmu.2016.00425

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Copyright © 2016 Abboud, Stanfield, Tahiliani, Desai, Hutchinson, Lorentsen, Cho, Avram and Salek-Ardakani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lack of Bcl11b in CD8 T cells does not alter disease symptoms, weight loss recovery, or survival after respiratory VacV-WR infection. WT (Bcl11b^flox/flox/dLck-iCre⁻) or Bcl11b-conditional knockout (Bcl11b^flox/flox/dLck-iCre⁺) mice were infected i.n. with VacV-WR (1.5 × 10⁴ PFU/mouse). Animals were weighed daily and euthanized if weight loss was greater than 25% body weight. Mean% of initial body weight from indicated numbers of mice is shown.