FIGURE 2.

Hydra’s experimental potential for studying interactions within the microbiome. Overview of the spectrum of microbial community study systems for unraveling interactions in the relatively simple Hydra microbiome. The integration of in vivo and in vitro experiments offers the opportunity to capture clues on how the host might affect microbe–microbe interactions and vice versa. The opportunity to study inter- and intra-specific interactions at different resolutions will help to unravel general principles of microbial interactions in microbiomes.