Table 1.
Sun‐MICRO | Sun‐MACRO | |||||
---|---|---|---|---|---|---|
Mean (SD) | All (n = 1056) | Placebo (n = 532) | Sulodexide (n = 524) | All (n = 843) | Placebo (n = 430) | Sulodexide (n = 413) |
Male, n (%) | 802 (75.9) | 408 (76.7) | 394 (75.2) | 645 (76.3) | 320 (74.2) | 325 (78.5) |
Age, years | 62.2 (9.8) | 62.3 (9.9) | 62 (9.7) | 62.9 (9.4) | 63.4 (9.6) | 62.3 (9.1) |
SBP, mmHg | 131.2 (11.8) | 131.5 (11.8) | 130.9 (11.8) | 137.9 (14.3) | 137.6 (14.6) | 138.2 (14.0) |
DBP, mmHg | 73.6 (11.9) | 73.4 (8.5) | 73.8 (8.7) | 73.2 (10.0) | 73.0 (10.1) | 73.4 (9.9) |
BMI, kg m–2 | 32.1 (5.5) | 31.9 (5.3) | 32.3 (5.7) | 32.8 (15.5) | 31.7 (6.3) | 34 (21.3) |
eGFR, ml min–1 1.73m–2 | 78.2 (22.4) | 77.9 (22.7) | 78.6 (22.1) | 33.4 (9.6) | 33.4 (9.7) | 33.4 (9.5) |
UACR, mg g–1 median (IQR) | 96 (54–141) | 95 (57–143) | 97 (55–141) | 1348 (648–2363) | 1238 (606–2305) | 1431 (704–2401) |
HbA1c, % | 7.6 (1.2) | 7.5 (1.3) | 7.6 (1.2) | 8.0 (1.6) | 7.9 (1.5) | 8.1 (1.7) |
BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HbA1c, glycosylated haemoglobin; IQR, interquartile range; SBP, systolic blood pressure; SD, standard deviation; Sun‐MACRO, sulodexide macroalbuminuria; Sun‐MICRO, sulodexide microalbuminuria; UACR, urine albumin‐to‐creatinine ratio