Table 1.
Patient demographics | Overall n = 32 | With morphine n = 19 | Without morphine n = 13 | P |
---|---|---|---|---|
Age (years) | 60 ± 11 | 58 ± 11 | 63 ± 10 | 0.17 |
Gender (male) n (%) | 29 (93) | 18 (94) | 11 (84) | 0.69 |
Risk factors/past medical history n (%) | ||||
Hypertension | 18 (62) | 10 (56) | 8 (72) | 0.36 |
Hyperlipidaemia | 10 (35) | 7 (39) | 3 (27) | 0.52 |
Smoking | 25 (86) | 15 (83) | 10 (91) | 0.57 |
Family history of CAD | 10 (34) | 9 (50) | 5 (38) | 0.25 |
Diabetes mellitus | 4 (14) | 3 (17) | 1 (9) | 0.57 |
Prior PCI | 4 (13) | 3 (18) | 1 (9) | 0.53 |
Prior myocardial infarction | 6 (21) | 4 (22) | 2 (18) | 0.80 |
Peripheral arterial occlusive disease | 3 (10) | 1 (6) | 2 (18) | 0.28 |
Cerebrovascular disease | 1 (3) | 1 (5) | 0 (0) | 0.43 |
Laboratory data (mean ± SD) | ||||
Platelet counts (×10 9 l –1 ) | 224 ± 67 | 222 ± 73 | 229 ± 61 | 0.90 |
C reactive protein (mg dl −1 ) | 0.83 ± 1.12 | 0.63 ± 1.14 | 1.16 ± 1.06 | 0.07 |
White blood cell count (×10 9 l –1 ) | 12.26 ± 3.56 | 12.27 ± 3.89 | 12.24 ± 3.07 | 0.80 |
Creatinine (mg dl −1 ) | 0.98 ± 0.27 | 1.02 ± 0.32 | 0.93 ± 0.18 | 0.64 |
Haemoglobin (g dl −1 ) | 14.9 ± 1.03 | 14.9 ± 0.86 | 14.9 ± 1.33 | 0.55 |
Fibrinogen (mg dl −1 ) | 384 ± 85 | 382 ± 76 | 386 ± 101 | 0.78 |
Concomitant medications at 2 h n (%) | ||||
Aspirin | 32 (100) | 19 (100) | 13 (100) | |
Proton pump inhibitors | 23 (80) | 15 (83) | 8 (73) | 0.49 |
β‐blockers | 23 (80) | 15 (83) | 8 (72) | 0.59 |
Statins | 25 (86) | 16 (90) | 9 (82) | 0.49 |
Angiotensin‐converting enzyme inhibitors | 23 (80) | 14 (78) | 9 (82) | 0.79 |
Calcium channel blockers | 3 (10) | 1 (6) | 2 (18) | 0.28 |
Angiographic data | ||||
GPIIbIIIa blocker (abciximab) during the PCI | 17 (57) | 11 (60) | 6 (55) | 0.78 |
Heparin | 32 (100) | 19 (100) | 13 (100) | |
Bivalirudin | 0 (0) | 0 (0) | 0 (0) | |
Primary PCI | 32 (100) | 19 (100) | 13 (100) | |
Number of stents per patient | 1.57 ± 1.19 | 1.79 ± 1.31 | 1.18 ± 0.87 | 0.23 |
Total stent length (mm) | 35.9636.0 ± 34.051 | 38.4 ± 40.0 | 30.8 ± 16.384 | 0.78 |
Data are reported as mean ± standard deviation (SD), n (number of patients) or percentages. CAD, coronary artery disease; GP, glycoprotein; PCI, percutaneous coronary intervention.