Table 1.
Linear correlation analysis of genes expression in different tissues in female and male mice.
| Genes: Bglap-Ngf-Ngf-Bdnf- vs. Gprc6a-Ngfr-Ntrk1-Ntrk2- | Equations | Correlation factor R2 |
|---|---|---|
| Brain | Male y = 0.5329x − 0.0156 | 0.917 |
| Female y = 0.6929x − 0.054 | 0.8908 | |
| WAT | Male y = 0.5896x + 0.3755 | 0.5446 |
| Female y = 0.1055x + 0.0376 | 0.5105 | |
| BAT | Male y = −0.5757x + 0.249 | 0.776 |
| Female y = 0.485x + 0.0209 | 0.8922 | |
| Bone | Male y = −0.1929x + 0.229 | 0.4505 |
| Female y = 0.0637x − 0.0028 | 0.3462 | |
| Testis | y = −2.185x + 0.557 | 0.7181 |
| Ovaries | y = −29.607x + 20.221 | 0.4911 |
| Uterus | y = 5.3416x + 3.9574 | 0.4712 |
Linear correlation analysis of gene expression was performed between the genes expressing ligands and their respective receptors in different tissues. An high correlation with R2 >0.5 was calculated in brain, BAT and testis in either male and female mice. The sample size was between 3 and 7 for each group.