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. 2016 Jul 20;41(12):2851–2861. doi: 10.1038/npp.2016.96

Figure 5.

Figure 5

Effect of NAc core MeCP2 knockdown on saccharin intake, extinction, and reinstatement. (a) Average number of saccharin reinforcements earned per 30-min SA session in sh-Control and sh-MeCP2 infused animals. *p⩽0.05 vs sh-Control. Average total number of active responses (b) and reinforcers (c) earned during progressive ratio tests following saccharin SA training. (d) Average number of active responses during the last 2 days of both SA (ie, SA Baseline) and extinction, and during cue-induced reinstatement. sh-Control (n=5) and sh-MeCP2 (n=5). Error bars indicate SEM.