Figure 2.

Kaplan–Meier plot of OS and PFS by treatment arm in the VEGFR2 high and low groups. Patients with VEGFR2 IHC results from neoplastic vessels were dichotomised into the high and low subgroups, based on their individual VEGFR2 levels relative to the median level for the population (H-score median=35). Kaplan–Meier plots for OS in patients in the (A) high VEGFR2 group (H-score ⩾35) and (B) low VEGFR2 group (H-score <35), and for PFS in the (C) high VEGFR2 group and (D) low VEGFR2 group are shown. Inset tables give median survival times (months) and 95% CIs. Abbreviations: CI, confidence interval; HR, hazard ratio; n, number of patients; PBO, placebo; RAM, ramucirumab; VEGFR2, vascular endothelial growth factor receptor 2.