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. 2016 Oct 13;9:101. doi: 10.3389/fnmol.2016.00101

Figure 3.

Figure 3

Influence of MPTP-induced DA depletion on phosphorylation of PKA and CREB. (A,B) Levels of D1-like receptors (D1R) and D2R mRNA in d-DG and v-DG on day 7 post-MPTP. (C,D) Bar graphs show the mean levels of PKA and CREB phosphorylation in d-DG and v-DG of MPTP-mice untreated or treated with SKF38393 (SKF, 10 mg/kg, i.p.), H89 (1 mg/kg, i.p.) or quinpirole (Quin, 2 mg/kg, i.p.) for 2 days and control mice untreated or treated with SCH23390 (SCH, 0.5 mg/kg, i.p.) or L-sulpiride (L-s, 15 mg/kg. i.p.) for 2 days. *p < 0.05 and **p < 0.01 vs. control mice; ##p < 0.01 vs. MPTP-mice; +p < 0.05 vs. MPTP-mice treated with SKF.