Figure 1.

Vagal cortical projection targets. (a) Tracer injections were made at vagal-evoked potential foci, which were generally located in the middle of VMb in different cases (colour coded). (b) One example (STM 158) is shown: the dark reaction product identifies the location of the WGA*HRP injection. (c) Dense middle-layer terminal projections (red) were found in two cortical regions: anterior insula (in the fundus of the superior limiting sulcus, focused posterior to its anterior end) and ventral precentral cortex (near the fundus of the inferior precentral sulcus, approx. 2–4 mm anterolateral to the end of the central sulcus). Two examples (STM158, STM172) are illustrated and a darkfield photomicrograph of the terminal labelling in each cortical region is shown. These illustrations are taken from Ito and Craig [64]. The inset (top right) shows the current architectural map of the macaque insula, taken directly from Craig [10] and modified from Evrard et al. [65]. WGA*HRP, wheat germ agglutinin-conjugated HRP.