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. 2016 Oct 10;7:12948. doi: 10.1038/ncomms12948

Figure 3. Elevation of the plasma NAD+ metabolome by oral NR in a 52-year-old male.

Figure 3

A healthy 52-year-old male ingested 1,000 mg NC Cl daily for 1 week. Plasma samples were prepared from blood collected before the first dose (0 h), at seven time points after the first dose (0.6, 1, 1.4, 2.7, 4.1, 7.7 and 8.1 h), before second dose (23.8 h) and 24 h after the seventh dose (167.6 h). Concentrations (a, Nam; b, MeNam; c, Me2PY; d, Me4PY) are with respect to whole blood volumes. The data indicate that plasma MeNam, Me4PY and Me2PY are strongly elevated by oral NR. No phosphorylated species were found in plasma.