Table 1.
Comparative epidemiological, clinical, and laboratory data of patients with AIDS-associated cryptococcosis
| Deaths (N = 45; mean age = 31.7) | Survivors (N = 24; mean age = 29.9) | P value | |||||
|---|---|---|---|---|---|---|---|
| Yes | No | % | Yes | No | % | ||
| Epidemiological features | |||||||
| Male | 35 | – | 77.8 | 23 | – | 95.8 | – |
| Female | 10 | – | 57.9 | 1 | – | 4.2 | – |
| Alcoholism | 28 | 17 | 75.7 | 21 | 3 | 87.5 | 0.0275 |
| Illicit drug user | 15 | 30 | 41.7 | 16 | 8 | 66.6 | 0.0080 |
| CD4+ T count < 100 cell/mm3 | 13 | 2 | 86.7 | 23 | 1 | 95.8 | 0.2959 |
| First AIDS defining condition | 15 | 30 | 33.3 | 6 | 18 | 25.0 | 0.4736 |
| Clinical and laboratorial features | |||||||
| Signs/symptoms < 10 days | 22 | 23 | 48.9 | 14 | 10 | 56.5 | 0.4544 |
| Fever | 39 | 6 | 86.7 | 20 | 4 | 83.3 | 0.7070 |
| Weight loss | 34 | 11 | 75.6 | 8 | 16 | 33.3 | 0.0006 |
| Altered consciousness | 23 | 22 | 52.3 | 4 | 20 | 16.7 | 0.0047 |
| Intracranial increased pressure | 23 | 22 | 52.3 | 6 | 18 | 25.0 | 0.0407 |
| CSF low cell count | 17 | 28 | 54.9 | 16 | 8 | 66.7 | 0.4175 |
| CSF low glucose | 28 | 17 | 90.3 | 17 | 7 | 70.8 | 0.6680 |
AIDS = acquired immunodeficiency syndrome; CSF = cerebrospinal fluid.