Table 2.
Correlation between plasma miRNA-195 expression and different clinicopathological features in patients with non-small cell lung cancer
| Clinicopathological features | No. of cases | Plasma miR-195 expression | P | |
|---|---|---|---|---|
| Low (n, %) | High (n, %) | |||
| Age | ||||
| <60 | 49 | 22(44.0 %) | 27(66.0 %) | 0.322 |
| ≥60 | 51 | 28(54.9 %) | 23(45.1 %) | |
| Gender | ||||
| Male | 65 | 34(52.3 %) | 31(47.7 %) | 0.338 |
| Female | 35 | 16(45.7 %) | 19(54.3 %) | |
| Histological type | ||||
| Squamous cell carcinoma | 46 | 25(54.3 %) | 21(45.7 %) | 0.701 |
| Adenocarcinoma | 44 | 20(45.5 %) | 24(54.5 %) | |
| Others | 10 | 5(50.0 %) | 5(50.0 %) | |
| Histological grade | ||||
| G1 + G2 | 55 | 26(47.3 %) | 29(52.7 %) | 0.688 |
| G3 | 45 | 24(53.3 %) | 21(46.7 %) | |
| Tumor size | ||||
| ≤3 cm | 38 | 16(42.1 %) | 22(57.9 %) | 0.151 |
| >3 cm | 62 | 34(54.8 %) | 28(45.2 %) | |
| N classification | ||||
| Positive | 63 | 39(61.9 %) | 24(28.1 %) | 0.002 |
| Negative | 37 | 11(29.7 %) | 26(70.3 %) | |
| TNM stage | ||||
| I + II | 57 | 17(29.8 %) | 40(70.2 %) | <0.001 |
| III | 43 | 33(76.7 %) | 10(23.3 %) | |