Table 2.
Definitions of Grading Parameters for the FNCLCC System [21]
| Parameter | Criterion |
|---|---|
| Tumour Differentiation | |
| Score 1 | Sarcoma closely resembling normal adult mesenchymal tissue (e.g., well-differentiated liposarcoma) |
| Score 2 | Sarcomas for which histologic typing is certain (e.g. myxoid liposarcoma) |
| Score 3 | Embryonal and undifferentiated sarcomas; sarcomas of uncertain type |
| Mitosis Count | |
| Score 1 | 0-9/10 HPF |
| Score 2 | 10-19/10 HPF |
| Score 3 | ≥20/10 HPF |
| Tumour Necrosis (Microscopic) | |
| Score 0 | No necrosis |
| Score 1 | ≤50 % tumour necrosis |
| Score 2 | >50 % tumour necrosis |
| Histologic Grade | |
| Grade 1 | Total score 2,3 |
| Grade 2 | Total score 4,5 |
| Grade 3 | Total score 6,7,8 |
FNCLCC Fédération Nationale de Centres de Lutte Contre le Cancer, HPF high-power field