Fig. 2.

A. cantonensis infection led to lymphoid organ atrophy and lymphopenia of mice at 21 dpi. a Images of the spleen and thymus of control and 21 dpi mice. Spleen weight and thymus weight at different time-points of infection. b Percentages and absolute numbers of splenic B cells, T cells, CD4⁺ T, and CD8⁺ T cells. c The absolute number of total B cells, T cells, CD4⁺ T cells, and CD8⁺ T cells in peripheral blood. d Splenic cells from control and 21 dpi mice were gated on CD3⁺ T cells first, followed by the analysis for Th1, Th2, and T regulatory cells. Each group of mice comprised five to six animals. Data presented is one of three independent experiments. Values were shown as mean ± SEM. A one-way ANOVA is used to test the equality of three or more means by using variances. Two-tailed t test was used for two samples comparison. *, results differed from the control group; *P < 0.05; **P < 0.01; ***P < 0.001