Table 1.
Baseline demographic and clinical characteristics according to spontaneous bacterial peritonitis
| Total (n = 102) | No SBP (n = 78) | SBP (n = 24) | p-value | |
|---|---|---|---|---|
| Age, years | 54.5 (45.8–62.8) | 53.0 (45.8–62.0) | 55.5 (45.8–68.5) | 0.376 |
| Gender, male | 73 (71.6 %) | 59 (75.6 %) | 14 (58.3 %) | 0.123 |
| Etiology | 0.983 | |||
| Alcohol | 66 (64.7 %) | 50 (64.1 %) | 16 (66.7 %) | |
| HBV | 18 (17.6 %) | 14 (17.9 %) | 4 (16.7 %) | |
| HCV | 12 (11.8 %) | 9 (11.5 %) | 3 (12.5 %) | |
| HBV + HCV | 1 (1.0 %) | 1 (1.3 %) | 0 (0 %) | |
| Others | 5 (4.9 %) | 4 (5.1 %) | 1 (4.2 %) | |
| Child-Pugh score | 11 (9–12) | 11 (9–12) | 11 (10–12) | 0.089 |
| Prior SBP | 19 (18.6 %) | 12 (15.4 %) | 7 (29.2 %) | 0.143 |
| Ascitic fluid level | ||||
| Lactoferrin (ng/ml) | 21.7 (0–100.1) | 0.6 (0–54.5) | 112.7 (91.5–139.8) | <0.001 |
| WBC (cells/ml) | 151 (60–416) | 100.5 (48.8–181.3) | 1158 (538–5651) | <0.001 |
| PMN (cells/ml) | 11.5 (4.0–98.0) | 6.5 (3.0–16.3) | 5695 (3660–9668) | <0.001 |
| Serum level | ||||
| WBC (×1000/μl) | 6.2 (4.7–9.8) | 5.9 (5.0–8.9) | 7.6 (5.5–11.8) | 0.037 |
| PMN (×1000/μl) | 3.9 (2.4–6.6) | 3.7 (2.3–5.6) | 5.7 (3.7–9.7) | 0.006 |
| Hemoglobin (g/dL) | 9.3 (8.5–10.8) | 9.3 (8.4–10.7) | 9.2 (8.6–10.9) | 0.862 |
| Platelet (×1000/μl) | 82.0 (50.0–127.8) | 90.5 (53.0–135.3) | 60.0 (47.3–105.5) | 0.053 |
| Albumin (g/dL) | 2.5 (2.3–2.8) | 2.6 (2.3–2.8) | 2.5 (2.3–2.6) | 0.190 |
| Bilirubin (g/dL) | 3.8 (2.0–7.8) | 3.6 (1.9–7.7) | 4.4 (2.3–12.7) | 0.289 |
| PT-INR | 1.61 (1.35–2.23) | 1.58 (1.33–2.07) | 1.97 (1.49–2.39) | 0.069 |
| CRP (mg/L) | 13.9 (6.7–21.9) | 11.0 (5.2–16.4) | 30.7 (18.7–68.1) | <0.001 |
Data are presented as the median (interquartile range) for continuous data and percentages for categorical data
SBP spontaneous bacterial peritonitis, HBV hepatitis B virus, HCV hepatitis C virus, WBC White blood cells, PMN Polymorphonuclear cell, PT-INR prothrombin time-international normalized ratio, CRP C-reactive protein