Table 1.
Clinical-pathological characteristics of studied groups of patients
| Characteristics | Testing set | Validation set I | Validation set II |
|---|---|---|---|
| (n = 52) | (n = 67) | (n = 32) | |
| Gender (male/female) | 36/16 | 45/22 | 19/13 |
| Age at diagnosisa | 63.9 ± 9.2 years | 70.2 ± 9.5 years | 70.8 ± 11.2 years |
| Tumor size (pT) | |||
| pT2 | 3 | - | 4 |
| pT3 | 40 | 62 | 24 |
| pT4 | 9 | 5 | 4 |
| Presence of lymph node metastasis (pN) | |||
| pN0 | 15 | 67 | 18 |
| pN1-2 | 37 | - | 14 |
| Presence of distant metastasis (pM) | |||
| pM0 | 26 | 67 | 32 |
| pM1 | 26 | - | - |
| Stage | |||
| UICC II | 8 | 67 | 18 |
| UICC III | 18 | - | 14 |
| UICC IV | 26 | - | - |
| Histological grade (G)b | |||
| GI | 6 | 9 | 6 |
| GII | 39 | 47 | 19 |
| GIII | 7 | 8 | 3 |
| Gx | - | 3 | 4 |
| Primary localization | |||
| Colon | 26 | 44 | 28 |
| Rectosigmoideum | 12 | 9 | 1 |
| Rectum | 14 | 14 | 3 |
| Chemotherapy | |||
| 5-FU-based | 52 | 24c | 17 |
| None | - | 33c | 15 |
Footnotes:
aMedian ± standard deviation
b GI well differentiated, GII moderately differentiated, GIII poorly differentiated, Gx cannot be assessed
cNumbers may not add up to 67 of available subjects because of missing data (n = 10)