Table 2.
Biomarker | Cutoff value | AUC (95% CI) | Sensitivity | Specificity | PPV | NPV | p value |
---|---|---|---|---|---|---|---|
suPAR (mg/dl) | ≥4.37 | 0.99 (0.93 to 1.0) | 97.5% | 90.0% | 90.7% | 97.3% | 0.001* |
Lactic acid (mmol/l) | ≥1.95 | 0.84 (0.74 to 0.91) | 67.5% | 87.5% | 84.4% | 72.9% | 0.001* |
Abbreviations: AUC, area under ROC (receiver operating characteristic) curve; CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value
*Highly significant difference