Table 3.
Multivariate Cox regression on disease-free interval for alignment of bedtime among 72 subjects with metastatic breast cancer.
| B | SE | χ2c | df | P | Hazard Ratio |
95% Confidence Interval |
|
|---|---|---|---|---|---|---|---|
| Age at initial diagnosisa | 0.024 | 0.018 | 1.664 | 1 | 0.197 | 1.024 | 0.988–1.061 |
| Estrogen receptor, negative | 0.774 | 0.335 | 4.813 | 1 | 0.028 | 2.169 | 1.124–4.187 |
| Natural-killer cell countb, lower | 0.496 | 0.253 | 3.830 | 1 | 0.050 | 1.641 | 1.000–2.695 |
| Chronotype (ref: neither type) | 5.467 | 2 | 0.065 | ||||
| Morning type | −0.618 | 0.265 | 5.328 | 1 | 0.021 | 0.539 | 0.320–0.906 |
| Evening type | −0.213 | 0.593 | 0.132 | 1 | 0.716 | 0.808 | 0.253–2.582 |
| Misalignment of bedtime, “going to bed later or earlier than preferred bedtime” |
1.157 | 0.446 | 5.645 | 1 | 0.018 | 3.180 | 1.327–7.616 |
a
Continuous variables.
b
Natural-killer cell count was classified into higher and lower one by median value of 116.97/mm3 (n = 72).
c
Likelihood ratio test was performed.