Table 1.

The plasma level of TNFα, IL‐1, and IL‐6 before and after the induction of endotoxemia in anesthetized rabbits

	Control	LPS	ALB	BT086
TNFα, pg/ml
−30 min	87 ± 196	0	0	0
+30 min	640 ± 994	1934 ± 2043	1449 ± 467	632 ± 384
+90 min	7179 ± 2080	4766 ± 3668	6913 ± 4046	5289 ± 6561
+180 min	61 ± 36	70 ± 91	118 ± 123	331 ± 564
IL‐1, pg/ml
−30 min	82.0 ± 25.6	68.0 ± 37.4	79.0 ± 35.5	95.3 ± 12.8
+30 min	80.7 ± 30.6	70.3 ± 36.8	74.4 ± 31.4	93.8 ± 5.3
+90 min	91.5 ± 20.8	87.8 ± 41.9	88.4 ± 28.2	114.6 ± 6.7
+180 min	110.2 ± 26.7	91.9 ± 37.1	100.5 ± 27.1	123.5 ± 16.2
IL‐6, pg/ml
−30 min	80.0 ± 34.2	56.3 ± 35.1	68.5 ± 20.5	97.4 ± 38.6
+30 min	78.8 ± 51.2	60.6 ± 32.9	75.4 ± 34.6	91.0 ± 26.5
+90 min	91.4 ± 39.9	79.7 ± 45.6	88.8 ± 28.0	102.5 ± 26.8
+180 min	101.2 ± 46.9	83.5 ± 41.3	95.6 ± 42.8	115.6 ± 45.7

The measurements of TNFα, IL‐1, and IL‐6 levels did not differ among the groups (all the data are the mean ± SD).