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. 2015 Nov 24;60(2):300–312. doi: 10.1002/mnfr.201500595

Table 1.

Alleviation of obesity and improvement in the levels of blood constituents by quercetin in mice fed a Western diet

Control diet Western diet Western diet+ 0.05% quercetin
Body weight (g) 35.66 ± 1.46a 45.77 ± 0.95b 41.69 ± 1.33c
Liver weight (g) 1.46 ± 0.08a 3.47 ± 0.28b 2.13 ± 0.19c
Kidney weight (g) 0.37 ± 0.01 0.36 ± 0.01 0.38 ± 0.01
Pancreas weight (g) 0.28 ± 0.02 0.30 ± 0.03 0.27 ± 0.02
Visceral fat (g/mouse) 2.25 ± 0.43a 4.34 ± 0.12b 3.33 ± 0.36a,b
Blood glucose (mg/dL) 143 ± 5a 224 ± 9b 151 ± 9a
Plasma insulin (ng/mL) 1.84 ± 0.47a 4.88 ± 0.67b 2.22 ± 0.32a
Plasma cholesterol (mg/dL) 76.2 ± 10.9a 194.0 ± 9.2b 123.3 ± 12.4c
Plasma leptin (ng/mL) 1.46 ± 0.61a 5.78 ± 0.58b 2.81 ± 0.51a
Plasma adiponectin (μg/mL) 4.42 ± 0.42a 2.87 ± 0.11b 3.18 ± 0.50a,b
Plasma resistin (ng/mL) 18.7 ± 1.2 22.2 ± 1.4 21.8 ± 1.2
Plasma TNFα (pg/mL) 13.2 ± 2.6a 34.9 ± 3.5b 19.9 ± 2.8a
Plasma IFNγ (pg/mL) 2.11 ± 0.33a 6.81 ± 1.3b 3.21 ± 0.58a

C57BL/6J mice were fed the control AIN93G diet or a Western diet containing either 0% or 0.05% quercetin for 18 weeks. Values are expressed as the mean ± SEM of 6–9 mice in each group. Different superscripts indicate significant differences (p < 0.05, two‐sided).