Table 1.
General characteristics of participants by CD36 rs6969989 genotype
| AA (n=1,760) | AG (n=1,952) | GG (n=498) | P-trend | |
|---|---|---|---|---|
| Age (yr) | 52.5±9.0 | 52.4±9.0 | 52.6±9.0 | 0.806 |
| Height (cm) | 153.7±5.6 | 153.9±5.5 | 154.1±5.3 | 0.503 |
| Weight (kg) | 59.0±8.3 | 59.1±8.7 | 59.0±8.5 | 0.732 |
| Waist (cm) | 81.5±9.4 | 81.5±9.7 | 81.7±10.2 | 0.981 |
| BMI (kg/m2) | 24.9±3.2 | 24.9±3.3 | 24.8±3.4 | 0.806 |
| Blood pressure (mmHg) | ||||
| Systolic | 116.8±19.9 | 117.3±19.4 | 116.6±19.2 | 0.589 |
| Diastolic | 73.8±12.4 | 73.7±11.9 | 73.5±11.7 | 0.799 |
| Current smokers (%) | 3.7 | 3.6 | 2.4 | 0.259 |
| Alcohol intake (g/d) | 1.4±5.7 | 1.0±4.0 | 1.5±6.7 | 0.334 |
| Exercise (MET-h/d) | 0.8±1.4 | 0.8±1.4 | 0.9±1.5 | 0.593 |
| High school education (%) | 32.2 | 33.1 | 33.6 | 0.490 |
| Hba1c (%) | 5.8±0.9 | 5.8±1.0 | 5.8±0.9 | 0.992 |
| Fasting glucose (mg/dL) | 85.2±20.4 | 85.7±20.7 | 83.3±15.4 | 0.013 |
| Fasting insulin (μIU/mL) | 7.9±4.6 | 8.2±5.3 | 7.9±5.6 | 0.263 |
| TC (mg/dL) | 191.4±35.8 | 191.7±35.7 | 191.8±35.0 | 0.979 |
| HDL-C (mg/dL) | 45.7±10.0 | 45.4±10.1 | 46.6±10.7 | 0.043 |
| LDL-C (mg/dL) | 116.5±32.4 | 116.5±31.6 | 115.4±31.8 | 0.735 |
| TG (mg/dL) | 146.0±81.5 | 149.1±93.6 | 149.0±88.0 | 0.540 |
| Dietary intake | ||||
| Energy (kcal) | 1,822.8±607.5 | 1,827.2±612.1 | 1,788.3±588.3 | 0.358 |
| Carbohydrate (%E) | 72.1±6.8 | 71.6±6.8 | 71.6±6.8 | 0.077 |
| Protein (%E) | 13.4±2.4 | 13.5±2.5 | 13.5±2.3 | 0.146 |
| Fat (%E) | 13.3±5.3 | 13.6±5.3 | 13.7±5.3 | 0.125 |
| CD36 rs6969989 G>A (MAF/HWE) | 0.12/0.22 | |||
Values are presented as mean±SD or percentage.
P-trend obtained in linear regression model and Cochran-Mantel-Haenszel analysis.
BMI, body mass index; MET, metabolic equivalent task; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride; MAF, minor allele frequency; HWE, Hardy-Weinberg equilibrium.