Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of Dormancy and Activation of PCa metastasis within the bone marrow niche. The bone marrow niche is a functionally dynamic component in the activity of metastatic cancer cells. PCa cells express receptors for CXCL12, Annexin2, and Gas6, which instigate dormancy and reduce mitotic activity. Conversely, dormant DTCs can be reactivated through external signals, such as Epo. PCa=Prostate Cancer; OBs=osteoblasts.
