TABLE 1.
Demographic, Clinical, and Tissue Characteristics of Human Subjects
| Measure | Nonpsychiatric Comparison Group (N=62) | Schizophrenia Group (N=62) | ||
|---|---|---|---|---|
| N | % | N | % | |
|
| ||||
| Male | 47 | 75.8 | 47 | 75.8 |
| Race | ||||
| White | 52 | 83.9 | 46 | 74.2 |
| Black | 10 | 16.1 | 16 | 25.8 |
|
| ||||
| Mean | SD | Mean | SD | |
|
| ||||
| Age (years) | 48.7 | 13.8 | 47.7 | 12.7 |
| Postmortem interval (hours) | 18.8 | 5.5 | 19.2 | 8.5 |
| Freezer storage time (months) | 131.8 | 56.2 | 128.1 | 60.7 |
| Brain pHa | 6.7 | 0.2 | 6.6 | 0.3 |
| RNA integrity number | 8.2 | 0.6 | 8.1 | 0.6 |
|
| ||||
| N | % | N | % | |
|
| ||||
| Medications at time of death | ||||
| Antipsychotic | 54 | 87.1 | ||
| Antidepressant | 27 | 43.5 | ||
| Benzodiazepine or anticonvulsant | 24 | 38.7 | ||
| Nonsteroidal anti-inflammatory drug | 13 | 20.0 | 16 | 25.8 |
a
Significant difference between groups, p=0.01.