Fig 4. Increased replacement of FcRnpos foetal-type epithelium by FcRnneg adult-type epithelium in the proximal parts of the SI after precociously induced maturation in rats.
(a) Immunohistochemistry of FcRn in representative histological sections (magnification 200x) from the proximal SI in 17 days old rats gavaged with PHA or protease for 3 days to induce precocious maturation, compared to control rats. (b) The proportion of adult-type FcRnneg enterocytes in the proximal SI epithelium (in % of total villous length) in 17 days old rats treated with PHA or protease, compared to control rats (mean ± SD, n = 6; *** p < 0.001).