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CDP, cytidine diphosphate; Cho, choline; DG, diacylglycerol; ER, endoplasmic reticulum; ETA, ethanolamine; p-ETA/p-Cho, phosphorylated ETA/choline; PM, plasma membrane; PS, phosphatidylserine. Mitochondrial PE deficiency causes mitochondrial defects, ER and cell wall stress, misprocessing of glycosylphosphatidylinositol-anchored proteins, accumulation of α-syn. Cardiolipin deficiency causes defects in mitochondrial bioenergetics [23].
