Fig 7. Phylogenetic relations between HIV sequences with PDR.

A Maximum Likelihood tree, built with the General Time Reversible + I + Γ model, without including drug resistance positions is shown. 1000 bootstrap repetitions were used to assess confidence. Viruses with PDR to PI (purple), NRTI (green), NNRTI (red) and more than one ARV class (blue) are colored. Reference sequences were obtained from Los Alamos HIV Database (bold). Five clusters of viral sequences with PDR with bootstrap values over 90% are amplified. Circle, females; empty triangle, heterosexual males; full triangle, self-identified men who have sex with men; square, unknown risk factor.