Fig 9. In-vivo imaging.

(A) Image showing the position of the surface coil that covers the abdomen (liver and part of the lungs) used for ¹⁹F-MRS, ¹⁹F-MRI, and ¹H-MRI. (B) Representative axial MRI of mice that received either SP (upper and middle panels) or T_act (lower panels). The livers can clearly be identified. The ¹⁹F-MRS spectra of these animals (SP middle panels and T_act lower panels) are illustrated in Fig 4. No images were acquired for mice injected with T_OVA-act. ¹H-MRI in grey and ¹⁹F-MRI in orange. The total ¹⁹F content in the liver of the animals measured by ex-vivo ¹⁹F-MRS was 1.5 x 10¹⁸ and 1.2 x 10¹⁸ after SP injection, and 1.15 x 10¹⁸ after T_act injection (compare also Fig 8B).