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Involvement of CHOP in enhanced cytotoxicity with a combination of BZ and VNR+AZM. Cell growth inhibition of wild-type MEF cell line and CHOP−/− cell line after treatment using VNR or PTX with/without BZ (25 nM) + AZM (50 μM) for 24 h. The viable cell number was assessed using CellTiter Blue assay as described in Materials and methods. *P<0.05; PTX vs. PTX+BZ+AZM, VNR vs. VNR+BZ+AZM.
